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The kinase activity of ATM can also be needed for its IR
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qabel4: hese two truncated forms of EGFR contain myc tickets at their C termini. We alsomade C terminal HA labeled SGLT1. We coexpressed HAlabeled SGLT1 with myctagged full size ICD or ECD of EGFRindependently in HEK293 cells. As shown in Figure 5F,...
In this sort of a system it is clear that ATM kinase action is necessary to phosphorylate a substrate and that ATM kinase activity and ATM mobilization are concomitant
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